CAGE1 and neuroblastoma: To evaluate the antitumor effects of CT3 CAR T cells in vivo, we generated an experimental metastatic NB model by inoculating luciferase-expressing IMR5 cells (IMR5-luc) into NOD/SCID/IL-2Rgcnull (NSG) mice intravenously (i.v.)via tail vein injection (Figure 6A).