On the other hand, monocytes from mothers with obesity (n = 3/time point) exhibited suppression of genes involved in interferon signaling (STAT1, GBP5, PSMB8) and response to reactive oxygen species (STRBP, HEBP2, TRAP1, TRPA1) (p value <0.001) with gestational age (Figure S5B). The gene discussed is GBP5; the disease is obesity due to melanocortin 4 receptor deficiency.