TG and preeclampsia: In addition, preeclampsia could deleteriously affect the liver [46]; consequently, both the liver TBG production and binding ability of TBG might be interfered [47], therefore raising the fraction of free thyroid hormones in serum, thus, overall, counteracting the decrease of the thyroid hormone caused by the impairment of thyroid synthesis, secretion, and metabolic transformation ability in the preeclamptic model.