LncRNA TSPOAP1-AS1 showed a significant correlation with the immune-related gene BTLA in 15 kinds of cancers, with a strong correlation in PAAD and CHOL (|r| > 0.8), and the other mainly significant immune genes included CD28 (in 18 types of cancer) and CD40LG (in 14 types of cancer) (Figure 6C). Here, CD28 is linked to cancer.