KCNK6 and breast carcinoma: Simultaneously, we observed via transwell cell invasion assay results, that overexpression of KCNK6 also promotes the invasive ability of breast cancer cell lines compared to control cells; whereas the opposite effect was observed following KCNK6 knockdown (∗∗∗P < 0.001; ****P < 0.0001; Figures 3G,H).