Lectin-reactive AFP (AFP-L3) and des-gamma-carboxy prothrombin (DCP) have also been proven to be useful biomarkers for HCC (Li et al., 2001; Volk et al., 2007) and increase the sensitivity compared to using AFP alone (Marrero et al., 2009; Wang et al., 2020). Here, AFP is linked to hepatocellular carcinoma.