We evaluated possible modifiers of immune evasion (CD274 that encodes PD-L1 and PDCD1LG2 that encodes PD-L2), and investigated how these ligands correlate with CD8B expression in ACC, revisiting TCGA cohort data and the molecular steroidogenic classification established by Zheng et al. Here, PDCD1LG2 is linked to adrenal cortex carcinoma.