Hspb7, Mb, Cox7a1, Fbp2, and Scara5 have all previously been identified as tumor suppressor genes (Naderi, 2018) in breast cancer (Braganza et al., 2019), non-small cell lung cancer (Zhao et al., 2019), gastric cancer (Li et al., 2013), sarcoma (Huangyang et al., 2020), and hepatocellular carcinoma (Huang et al., 2010), wherein they can suppress tumor cell invasion, proliferation, and migration. The gene discussed is SCARA5; the disease is hepatocellular carcinoma.