Hspb7, Mb, Cox7a1, Fbp2, and Scara5 have all previously been identified as tumor suppressor genes (Naderi, 2018) in breast cancer (Braganza et al., 2019), non-small cell lung cancer (Zhao et al., 2019), gastric cancer (Li et al., 2013), sarcoma (Huangyang et al., 2020), and hepatocellular carcinoma (Huang et al., 2010), wherein they can suppress tumor cell invasion, proliferation, and migration. This evidence concerns the gene COX7A1 and hepatocellular carcinoma.