HPCA and Alzheimer disease: Among the 35 genes, previous studies have reported that the expressions of IFITM3 (Correani et al., 2017), SORBS1 (Blalock et al., 2004), ENAH (de Oliveira-Júnior et al., 2015), SST (Solarski et al., 2018), ENSA (Boettcher et al., 2008), C14orf40 (Chung et al., 2018), BASP1 (Zhou et al., 2020), RTN3 (Zou et al., 2018), CDK7 (Zhu et al., 2000), and HPCA (Jiang et al., 2016) were associated with AD or have functions in neural tissue, indicating possible therapeutic targets.