ACHE and Alzheimer disease: The current standards of care for the treatment of AD include therapies targeting the disturbances of the cholinergic and glutamatergic systems using drugs, such as donepezil (Aricept®), a reversible acetylcholinesterase inhibitor, and memantine (Ebixa®), an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, or a combination of these agents (Namzaric®) (Ferreira-Vieira et al., 2016; Arvanitakis et al., 2019; Conway, 2020).