They found that these combined modalities were able to differentiate glioma grade (AUC 0.852), ATRX mutation (AUC 0.851), MGMT mutation (AUC 0.757), IDH1 mutation (AUC 0.887), and 1p19q codeletion (AUC 0.978). This evidence concerns the gene ATRX and central nervous system cancer.