Our group and others have demonstrated that ZIKV infection in immunocompetent mice can lead to induction of CD8 T cell immunity, featuring the production of key effector cytokines such as IFN-γ or TNF-α, and the cytolytic molecule granzyme B, suggesting they are important for ZIKV immunity22,25. The gene discussed is GZMB; the disease is Zika virus infectious disease.