For example, for a Han Chinese patient, a panel encompassing newborn ovary homeobox protein (NOBOX), folliculogenesis specific BHLH transcription factor (FIGLA), basonuclin 1 (BNC1), spermatogenesis and oogenesis specific basic helix-loop -helix 1 (SOHLH1), SOHLH2, FOXO3 and HFM1 may be ordered to identify patients susceptible to ovarian failure after chemotherapy that might not be apparent otherwise (Fig. 2). Here, BNC1 is linked to ovarian dysfunction.