In addition, AP-2α expression was significantly higher in poorly differentiated HCC than in highly differentiated HCC, and AP-2α expression was positive in a significantly higher percentage of patients with high POSTN expression (56/72, 77.8%) than in patients with low POSTN expression (10/38, 26.3%) (Fig. 7A-B). This evidence concerns the gene POSTN and hepatocellular carcinoma.