STAT3 and Peritoneal Fibrosis: To date, activation of STAT3 signaling in peritoneal fibrosis had been reported only in some studies [14, 28, 29], activation of STAT3 signaling in the mesothelial cells induced by high glucose has been reported only in one study [16], but the role of STAT3 inhibitor in the pathogenesis of peritoneal fibrosis and potential molecules involved were still not fully understood.