CCAR2 and colorectal carcinoma: In addition, except for the LS411N cell line (from poorly differentiated CRC patient), the expression of CCAR2 mRNA in CRC cell lines of patients with Ducks' type B was significantly lower than that of patients with Ducks' type C-D, indicating that CCAR2 may be related to the progression and malignant degree of CRC (Fig. 9C).