Furthermore, we addressed the question whether analyzing a larger part of the LN volume improves detection of aggressive tumor cells by comparing detection of CEACAM5, KLK6, and SLC35D3 mRNAs in the entire volume of half a LN with the small volume of 8 consecutive 10-μm sections from the other half of the LN. The gene discussed is SLC35D3; the disease is neoplasm.