Elevated ICAM-1 level of ≥347ng/ml demonstrated an OR of 41.69; CI, 3.76–461.97; p = 0.002, whilst high Lp(a) level of ≥75 nmol/L showed an OR of 35.12; CI, 3.47–355.40; p = 0.003) for NAFLD. Here, LPA is linked to metabolic dysfunction-associated steatotic liver disease.