These include but are not limited to IRS 1 [19], GLUT4 [20], glycogen synthetase [21], UCP-3 [22], PI3-Kinase [23], hexokinase II [24], MAPK [23], Rad genes [25], serine-threonine kinases [26], calpain-10 [27] etc. In addition, during the last few years, several species of non-coding RNAs (ncRNAs) have been identified to depict altered signatures in the skeletal muscle during diabetes [28–30], and these have provided new evidences on their important regulatory roles in this tissue. Here, SLC2A4 is linked to diabetes mellitus.