There were 205 studies (45,726 LC cases and 58,788 controls for the GSTM1 null genotype, 103 studies (29,476 LC cases and 35,305 controls) for the GSTT1 null genotype, 69 studies (18,852 LC cases and 21,941 controls) for the GSTP1 IIe105Val polymorphism, and so on. This evidence concerns the gene GSTM1 and laryngotracheoesophageal cleft.