GPT and anemia: Individual AEs occurring in ≥ 50% of patients were anaemia (3/6 and 7/12 in levels 1 and 2, respectively), nausea (6/6 and 11/12), decreased appetite (6/6 and 7/12), vomiting (4/6 and 8/12), stomatitis (3/6 and 7/12), alanine aminotransferase (ALT) increased (4/6 and 12/12), aspartate aminotransferase (AST) increased (3/6 and 12/12), gamma-glutamyltransferase increased (2/6 and 7/12), neutrophil count decreased (6/6 and 11/12), platelet count decreased (2/6 and 7/12), and white blood cell count decreased (5/6 and 9/12).