ALPL and hypophosphatasia: The mutation in case 1 (c.318G > C; p.Gln106His) was previously reported in two neonates presenting with perinatal HPP and neonatal epileptic encephalopathy, as well as another ALPL variant.(20, 21) The mutation in case 2 (c.407G > A, pArg136His) was reported in one patient with infantile HPP and another with odonto‐HPP.(22, 23)