GAS5 and colorectal carcinoma: found that lncRNA GAS5 has a direct interacting process using YAP’s WW domain for facilitating endogenous YAP’s translocating process (the nucleus to the cytoplasm), as well as facilitating the phosphorylating process and then YAP degradation under mediation from ubiquitin for the in vitro and in vivo inhibiting CRC progressing process.