Another study involving adeno‐associated virus (AAV) delivery of CRISPR plasmid to model p53, KRAS and LKB1 genes in lung adenocarcinoma caused mutation in p53 and LKB1, resulting in loss of function in these genes, followed by the formation of adenocarcinoma pathology mediated by homology‐driven repair of KRAS G12D mutations.24 The gene discussed is TP53; the disease is lung adenocarcinoma.