The generation of an echinoderm microtubule‐associated protein‐like 4 gene fused to the anaplastic lymphoma kinase gene (Eml4‐Alk), which drives lung cancer mouse model, expressing the Eml4‐Alk fusion gene, shows the typical molecular and histopathological features of the human ALK+ non‐small‐cell lung cancer (NSCLC)27; such an approach can be modelled to investigate other genes implicated in the aetiology of other cancer types. The gene discussed is EML4; the disease is lung carcinoma.