After screening out RBPs related to prognosis, the expression of these RBPs of normal colon tissue and tumor tissue was validated by Human Protein Atlas (HPA): the levels of antibody staining of TDRD5 and LIN28B were significantly higher and the levels of antibody staining of PNLDC1, TDRD7, and LRRFIP2 were significantly weaker (Figure 5). The gene discussed is TDRD5; the disease is neoplasm.