Secondly, overexpressed TIPE1 could increase the protein level of E-Cadherin but decrease the protein level of N-Cadherin, Slug, and Snail, indicating that overexpressed TIPE1 could inhibit the epithelial-mesenchymal transition of ovarian cancer cells (Figure 2(b)). The gene discussed is SNAI2; the disease is ovarian carcinoma.