Hirokawa et al.40 reported that AP3D1-DOT1L-SF3A2 was identified as a new susceptibility locus for myocardial infarction (MI) by European genome-wide association studies (GWAS), which is consistent with our observation that s-AP3D1-Abs levels were significantly higher in patients with CVD including MI (Fig. 3a, Table 3). This evidence concerns the gene AP3D1 and myocardial infarction.