A positive correlation between USP51 and DGCR8 was observed in these breast carcinomas, in which 73% (61 of 83) of the tumors with moderate or weak DGCR8 expression exhibited moderate or weak USP51 expression, and 75% (42 of 56) of the tumors with strong DGCR8 expression showed strong USP51 expression (Spearman correlation R = 0.48, P = 3 × 10−9; Supplementary Fig. 7a, b). The gene discussed is USP51; the disease is breast carcinoma.