RHOB and breast cancer: Low mRNA expression of RhoB also significantly correlated with poor prognosis for HER2high and HER2high/CNKSR1high breast cancer patients (Fig 5F; P = 0.00089, high: n = 172, low: n = 304, Fig 5G; P = 0.021, high: n = 92, low: n = 146, respectively).