To determine the mechanism underlying CCSER1 role in oncogenesis, we relied again on the TCGA dataset, and compared and contrasted the transcriptomic profile of tumours with or without FDs at CCSER1. A functional enrichment analysis revealed that the most frequently altered pathways in tumours where the CCSER1 locus is deleted were related to mitosis and cell division (Fig 3B). The gene discussed is CCSER1; the disease is neoplasm.