The prominent involvement of top common enriched hub genes (Table 2) in MAP kinase signaling cascade, particularly in the JNK pathway, had led us to analyze the gene expression of JNK (MAPK8) and its major regulators, namely, ecotropic viral integration site 1 (EVI1), Dual-specificity phosphatase-1 (DUSP 1/MKP), and Protein tyrosine phosphatase receptor-type R (PTPRR) in ATLL patients and healthy subjects to validate the results of the meta-analysis. The gene discussed is MECOM; the disease is adult T-cell leukemia/lymphoma.