Besides, miR-93-5p inhibition abolished the effects of lncRNA XIST knockdown, thus promoting renal interstitial fibrosis in DN mice and HG-induced human kidney cells (HK-2) [16]. Consistent with these findings, our data presented that miR-93-5p restoration inhibited HG-induced HGMC proliferation, fibrosis and inflammation, while miR-93-5p inhibition promoted these dysfunctions that were blocked by HCP5 knockdown. The gene discussed is HCP5; the disease is liver dysplastic nodule.