On immunohistochemical staining using anti-human CXCR4 mouse monoclonal antibody (clone 44716) and anti-human/mouse CXCL12/SDF-1 mouse monoclonal antibody (clone 79018), DLBCL cells were positive for CXCR4 (Fig. 2d) and adenocarcinoma cells were positive for CXCL12/SDF-1 (Fig. 2e). Here, CXCR4 is linked to diffuse large B-cell lymphoma.