Finally, six lncRNAs (DLEU2, HOTTIP, MALAT1, NEAT1, SNHG1, and TUG1), registered in Lnc2Cancer 2.0, a database offering comprehensive experimentally supported associations between lncRNA and human cancer, were selected as candidate lncRNAs for the diagnosis of HCC (Fig. 1H). This evidence concerns the gene HOTTIP and hepatocellular carcinoma.