In cell culture, EPO expression was reduced in SARS-CoV-2 infected VeroE6 cells, consistently with the RNA-seq data of Blanco-Melo et al. in A549 cells (S7 Fig in S2 File; [38]), in contrast to other hypoxia markers (GLUT1, VEGFA) that were increased upon viral infection. This evidence concerns the gene EPO and viral infectious disease.