STAT6 and Hepatic fibrosis: Rahoud and team [35] also indicated the C allele, or the C/C and C/T genotypes to be associated with a higher risk in developing hepatic fibrosis in Sudanese patients; whilst He and colleagues in 2008 [15] showed through studying the STAT-6 gene (which is located in the IL-13 gene promoter) that, subjects with the C/T genotype were at a higher predisposition to S. haematobium infection.