IGF1R and posterior cortical atrophy: Western blotting revealed that PCAT6 knockdown significantly suppressed the activity of the PI3K/AKT and NF‐κB pathways and IGF1R overexpression attenuated the suppression induced by PCAT6 knockdown in PCa cells (Figure 6A), which indicated that IGF1R mediated the effect of PCAT6 on PI3K/AKT and NF‐κB pathways.