ALKBH5 and posterior cortical atrophy: Intriguingly, there was a positive correlation between METTL3 and PCAT6 levels in PCa tissues from the TCGA dataset, supporting the positive regulatory mechanism of METTL3 on PCAT6 (Figure 7F); concurrently, ALKBH5 (the demethylase of m6A) overexpression significantly reduced PCAT6 expression in PCa cells (Figure S7e).