Therefore, we performed RT‐qPCR assays to identify target mRNAs that were regulated by both PCAT6 and IGF2BP2 in these tumor‐related mRNAs and found that IGF1R was the most downregulated mRNA both in PCAT6‐ and IGF2BP2‐knockdown PC‐3 cells compared with control PC‐3 cells (Figure 5A and Figure S5a). This evidence concerns the gene IGF2BP2 and neoplasm.