The immunosuppressive TME in epithelial GC consist of infiltrating CD4+ T‐reg, CXCL13+ Th cells, CCL20lo/CD163hi, and APOE+ macrophages; however, it is the immune‐desert phenotype for gallbladder NET. The gene discussed is CXCL13; the disease is gallbladder neuroendocrine tumor, grade 1/2.