Interestingly, while Mir146a/b−/− mice had less prominent Th2 responses in airway inflammation models involving HDM as an allergen, the application of CPP‐miR‐146a nanocomplexes led to general anti‐inflammatory effects in allergic airway inflammation, suggesting therapeutic potential for these nanocomplexes (Figure 9). This evidence concerns the gene MIR146A and inflammatory response.