While HSD17B7‐dependent zymosterol and cholesterol production can therefore have a direct impact on mitochondria, they could also function as part of a bidirectional mitocellular communication network (Mottis et al, 2019), which has also been implicated in cancer disparities among populations with different ancestries (Choudhury & Singh, 2017). Here, HSD17B7 is linked to cancer.