), FAP, polymerase-proofreading-associated polyposis (PPAP), Lynch syndrome, Peutz–Jeghers syndrome (PJS), juvenile polyposis syndrome (JPS), Cowden syndrome (CS)/PTEN hamartoma tumor syndrome (PHTS), and Li–Fraumeni syndrome (LFS) are the autosomal dominant modes of inheritance. The gene discussed is FAP; the disease is juvenile polyposis syndrome.