As expected, the most significant liver disease association was identified at a previously reported missense variant (PNPLA3, rs738409) having increased risks with multiple liver disease conditions including NASH‐NAFLD composite (odds ratio [OR] = 1.713, p = 6.21 × 10−136) and fibrosis/cirrhosis (OR = 1.484, p = 2.99 × 10−115) (Tables S3 and S4). Here, PNPLA3 is linked to metabolic dysfunction-associated steatohepatitis.