Among the novel liver enzyme associations, a missense variant (rs3816873, p.I128T, pALT = 4.15 × 10−15, pAST = 3.16 × 10−12) in the gene microsomal triglyceride transfer protein (MTTP) has the most significant association with liver disease traits (NASH NAFLD composite, OR = 0.921, p = 3.33 × 10−5) (Figure S4 and Table S3). The gene discussed is MTTP; the disease is metabolic dysfunction-associated steatotic liver disease.