More recent evaluations of multiple apoptosis-related markers (e.g. BAX, cytochrome c, caspase-9, cleaved caspase-3) suggest apoptosis occurs in only a minority of RP models (Arango-Gonzalez et al., 2014; Sancho-Pelluz et al., 2008). Here, CASP3 is linked to retinitis pigmentosa 1.