People with T1D (adults and children; could also be appropriate for hard-to-control T2D)Sensor-augmented pump therapy with automatic low glucose suspend may be considered to prevent/mitigate episodes of hypoglycaemiaAutomated insulin delivery systems should be considered in adults with T1D who have the skills to use them to improve time in range, and reduce A1C/hypoglycaemia; may also be useful to improve glycaemia in children. This evidence concerns the gene INS and type 1 diabetes mellitus.