We compared the predicted regulon targets of SOX11 from the GRN analysis and the list of DEGs in the Tcf4KO. Comparison of the datasets yielded a list of 72 genes (Fig. 5B, Table S6), which was enriched for genes linked to autism spectrum disorders (e.g. POU3F2) and intellectual disability (e.g. DCX) (Fig. 5C) (Pilz et al., 1998; Martin et al., 2007). The gene discussed is DCX; the disease is Intellectual disability.