IL18 and pancreatic intraductal papillary-mucinous neoplasm: This murine model mechanistically showed NLRP3-regulated IL-18-induced eosinophil accumulation and degranulation, merged pancreatic ducts, pancreatic intraepithelial neoplasia 1 (PanIN1), PanIN2, PanIN3, and intraductal papillary mucinous neoplasm (IPMN).