KEGG pathway mainly including NF-KB signaling pathway, PI3K-Akt signaling pathway, focal adhesion, metabolic pathways, nucleotide excision repair, epstein-Barr virus infection, small cell lung cancer, ECM-receptor interaction, DNA replication, and chronic myeloid leukemia (Fig. 2B). Here, AKT1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.