VEGF has been shown to inhibit the expression of ICAM1 and VCAM1 on endothelial cells.33–35 Both proteins play a pivotal role in the extravasation of immune cells from the blood circulation by increasing vessel wall interaction with immune cells.33–35 These interactions have been extensively studied in tumor angiogenesis.33–35 We thus investigated whether extravasation of immune cells was associated with increased expression of ICAM1 and VCAM1. This evidence concerns the gene VEGFA and neoplasm.