SERPINA1 and colorectal carcinoma: In Arabidopsis, CRC was also demonstrated to be a direct target of AP3 and PI (Bowman and Smyth, 1999; Lee et al., 2005a; Wuest et al., 2012), the third/fourth whorl organs are not properly fused and deformed in ap3 or pi mutants but less evident than doll1 in Physalis, which is possibly due to the shortness of the style (Bowman and Smyth, 1999).