POMC and neoplasm: In one with negative [68Ga]Ga-DOTA-TATE uptake, ectopic source of tumor was not shown on any imaging modality, ectopic tumor ACTH production was diagnosed biochemically and on basis of complete resection of pituitary tissue (shown on MRI) as well absent pituitary [68Ga]Ga-DOTA-TATE activity (Fig. 3).